Anti-Glucose 6 phosphatase 2 antibody (ab66397)

Overview

  • Product nameAnti-Glucose 6 phosphatase 2 antibody
  • Description
    Rabbit polyclonal to Glucose 6 phosphatase 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Mouse IGRP.

  • Positive control
    • This antibody gave a positive signal in Mouse pancreas tissue lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab66397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).

Abcam recommends using 5% BSA as the blocking agent.

Target

  • RelevanceIGRP (islet specific glucose 6 phosphatase catalytic subunit related protein), also known as G6PC2, belongs to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyses the hydrolysis of glucose-6-phosphate. This hydrolysis is the terminal step in gluconeogenic and glycogenolytic pathways, and allows the release of glucose into the bloodstream. IGRP is found in pancreatic islets and does not exhibit phosphohydrolase activity. However, it is a major target of cell-mediated autoimmunity in diabetes.
  • Cellular localizationCell Membrane
  • Database links
  • Alternative names
    • G 6 Pase 2 antibody
    • G 6 Pase2 antibody
    • G6Pase 2 antibody
    • G6Pase2 antibody
    • G6PC 2 antibody
    • G6pc rs antibody
    • G6pcrs antibody
    • Glucose 6 phosphatase 2 antibody
    • Glucose 6 phosphatase, catalytic, 2 antibody
    • Glucose 6 phosphatase, catalytic, related antibody
    • Glucose 6 phosphate catalytic 2 antibody
    • Islet specific G6CP related protein antibody
    • Islet specific glucose 6 phosphatase antibody
    • Islet specific glucose 6 phosphatase catalytic subunit related protein antibody
    see all

Anti-Glucose 6 phosphatase 2 antibody images

  • Anti-Glucose 6 phosphatase 2 antibody (ab66397) at 1 µg/ml + Pancreas (Mouse) Tissue Lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 29 kDa,58 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

References for Anti-Glucose 6 phosphatase 2 antibody (ab66397)

ab66397 has not yet been referenced specifically in any publications.

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