Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab84087)

Overview

  • Product nameAnti-Glucose 6 Phosphate Dehydrogenase antibody
    See all Glucose 6 Phosphate Dehydrogenase primary antibodies
  • Description
    Rabbit polyclonal to Glucose 6 Phosphate Dehydrogenase
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Chimpanzee, Baboon, Rhesus monkey, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to a region within the amino acids 50-100 of Human Glucose 6 Phosphate Dehydrogenase, NP_000393.2

  • Positive control
    • Human stomach adenocarcinoma tissue. Mouse liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab84087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate or Tris-EDTA (pH 9.0) buffer will enhance staining.
    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCatalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
    • Tissue specificityIsoform Long is found in lymphoblasts, granulocytes and sperm.
    • PathwayCarbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
    • Involvement in diseaseAnemia, non-spherocytic hemolytic, due to G6PD deficiency
    • Sequence similaritiesBelongs to the glucose-6-phosphate dehydrogenase family.
    • Post-translational
      modifications
      Acetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.
    • Information by UniProt
    • Database links
    • Alternative names
      • G6PD antibody
      • G6PD_HUMAN antibody
      • G6PD1 antibody
      • G6pdx antibody
      • Glucose 6 phosphate 1 dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase, G6PD antibody
      • Glucose-6-phosphate 1-dehydrogenase antibody
      • MET19 antibody
      • POS10 antibody
      • Zwf1p antibody
      see all

    Anti-Glucose 6 Phosphate Dehydrogenase antibody images

    • Detection of Human Glucose 6 Phosphate Dehydrogenase by Immunohistochemistry.
      Samples: FFPE section of Human stomach adenocarcinoma.
      Antibody: ab84087 used at a dilution of 1/500.
      Detection: DAB.
    • Detection of Mouse Glucose 6 Phosphate Dehydrogenase by Immunohistochemistry.
      Samples: FFPE section of Mouse liver.
      Antibody: ab84087 used at a dilution of 1/250.
      Detection: DAB.

    References for Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab84087)

    ab84087 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"