Anti-Glucose 6 Phosphate Dehydrogenase antibody (Biotin) (ab20606)

Submit an Abreview Submit a Question Specific References (1)

Overview

  • Product name
    Anti-Glucose 6 Phosphate Dehydrogenase antibody (Biotin)
    See all Glucose 6 Phosphate Dehydrogenase primary antibodies
  • Description
    Goat polyclonal to Glucose 6 Phosphate Dehydrogenase (Biotin)
  • Host species
    Goat
  • Conjugation
    Biotin
  • Specificity
    This antibody is specific to purified and partially purified Glucose 6 Phosphate Dehydrogenase (Leuconostoc mesenteroides).
  • Tested applications
    Suitable for: ELISAmore details
  • Species reactivity
    Reacts with Leuconostoc mesenteroides. Not yet tested in other species.
  • Immunogen

    Glucose 6 Phosphate Dehydrogenase (Leuconostoc mesenteroides).

Properties

Applications

Our Abpromise guarantee covers the use of ab20606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000 - 1/5000.

Target

  • Function
    Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
  • Tissue specificity
    Isoform Long is found in lymphoblasts, granulocytes and sperm.
  • Pathway
    Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
  • Involvement in disease
    Anemia, non-spherocytic hemolytic, due to G6PD deficiency
  • Sequence similarities
    Belongs to the glucose-6-phosphate dehydrogenase family.
  • Post-translational
    modifications
    Acetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.
  • Information by UniProt
  • Alternative names
    • G6PD antibody
    • G6PD_HUMAN antibody
    • G6PD1 antibody
    • G6pdx antibody
    • Glucose 6 phosphate 1 dehydrogenase antibody
    • Glucose 6 phosphate dehydrogenase antibody
    • Glucose 6 phosphate dehydrogenase, G6PD antibody
    • Glucose-6-phosphate 1-dehydrogenase antibody
    • MET19 antibody
    • POS10 antibody
    • Zwf1p antibody
    see all

References

This product has been referenced in:
  • Mandal K  et al. An integrated transcriptomics-guided genome-wide promoter analysis and next-generation proteomics approach to mine factor(s) regulating cellular differentiation. DNA Res 24:143-157 (2017). Read more (PubMed: 28065881) »

See 1 Publication for this product

Publishing research using ab20606? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Submit a review Submit a question

There are currently no Customer reviews or Questions for ab20606.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up