Anti-Glucose 6 Phosphate Dehydrogenase antibody (Biotin) (ab20606)

Overview

• Product nameAnti-Glucose 6 Phosphate Dehydrogenase antibody (Biotin)
  See all Glucose 6 Phosphate Dehydrogenase primary antibodies
• Description
  Goat polyclonal to Glucose 6 Phosphate Dehydrogenase (Biotin)
• ConjugationBiotin
• SpecificityThis antibody is specific to purified and partially purified Glucose 6 Phosphate Dehydrogenase (Leuconostoc mesenteroides).
• Tested applicationsSuitable for: ELISAmore details
• Species reactivity
  Reacts with Leuconostoc mesenteroides. Not yet tested in other species.
• Immunogen

  Glucose 6 Phosphate Dehydrogenase (Leuconostoc mesenteroides).

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• Storage bufferPreservative: 0.01% Sodium Azide
  Constituents: PBS, pH 7.2
• Concentration information loading...
• Purification notesPurified from monospecific antiserum by delipidation, fractionation and ion exchange chromatography.
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cardiovascular
  • Atherosclerosis
  • Diabetes associated

  • Cardiovascular
  • Heart
  • Cardiac metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Types of disease
  • Diabetes

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Types of disease
  • Heart disease

Associated products

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

Applications

Target

• FunctionCatalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
• Tissue specificityIsoform Long is found in lymphoblasts, granulocytes and sperm.
• PathwayCarbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
• Involvement in diseaseAnemia, non-spherocytic hemolytic, due to G6PD deficiency
• Sequence similaritiesBelongs to the glucose-6-phosphate dehydrogenase family.
• Post-translational
  modificationsAcetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.

• Target information above from: UniProt accession P11413 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Alternative names
  • G6PD antibody
  • G6PD_HUMAN antibody
  • G6PD1 antibody

  • G6pdx antibody
  • Glucose 6 phosphate 1 dehydrogenase antibody
  • Glucose 6 phosphate dehydrogenase antibody
  • Glucose 6 phosphate dehydrogenase, G6PD antibody
  • Glucose-6-phosphate 1-dehydrogenase antibody
  • MET19 antibody
  • POS10 antibody
  • Zwf1p antibody

  see all