Anti-Glutamyl hydrolase gamma antibody (ab110074)

Overview

  • Product nameAnti-Glutamyl hydrolase gamma antibody
    See all Glutamyl hydrolase gamma primary antibodies
  • Description
    Rabbit polyclonal to Glutamyl hydrolase gamma
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A synthesized peptide derived from an internal region of Human Glutamyl hydrolase gamma.

  • Positive control
    • Extracts from RAW264.7 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab110074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 36 kDa.

Target

  • FunctionHydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
  • Sequence similaritiesBelongs to the peptidase C26 family.
    Contains 1 gamma-glutamyl hydrolase domain.
  • Cellular localizationSecreted > extracellular space. Lysosome. Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Database links
  • Alternative names
    • Conjugase antibody
    • folylpolygammaglutamyl hydrolase antibody
    • gamma glutamyl hydrolase antibody
    • Gamma-Glu-X carboxypeptidase antibody
    • Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) antibody
    • Gamma-glutamyl hydrolase antibody
    • GGH antibody
    • GGH_HUMAN antibody
    • gH antibody
    see all

Anti-Glutamyl hydrolase gamma antibody images

  • All lanes : Anti-Glutamyl hydrolase gamma antibody (ab110074) at 1/500 dilution

    Lane 1 : Extracts from RAW264.7
    Lane 2 : Extracts from RAW264.7 with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 36 kDa

References for Anti-Glutamyl hydrolase gamma antibody (ab110074)

ab110074 has not yet been referenced specifically in any publications.

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