Anti-Glutamyl hydrolase gamma antibody (ab125473)

Overview

  • Product nameAnti-Glutamyl hydrolase gamma antibody
    See all Glutamyl hydrolase gamma primary antibodies
  • Description
    Rabbit polyclonal to Glutamyl hydrolase gamma
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to a region within the C-terminal amino acids 256-305 (DGISHAPNAV KTAFYLAEFF VNEARKNNHH FKSESEEEKA LIYQFSPIYT) of Human Glutamyl hydrolase gamma (NP_003869).

  • Positive control
    • Human Fetal Kidney Lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionHydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
  • Sequence similaritiesBelongs to the peptidase C26 family.
    Contains 1 gamma-glutamyl hydrolase domain.
  • Cellular localizationSecreted > extracellular space. Lysosome. Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Database links
  • Alternative names
    • Conjugase antibody
    • folylpolygammaglutamyl hydrolase antibody
    • gamma glutamyl hydrolase antibody
    • Gamma-Glu-X carboxypeptidase antibody
    • Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) antibody
    • Gamma-glutamyl hydrolase antibody
    • GGH antibody
    • GGH_HUMAN antibody
    • gH antibody
    see all

Anti-Glutamyl hydrolase gamma antibody images

  • Anti-Glutamyl hydrolase gamma antibody (ab125473) at 1 µg/ml + Human Fetal Kidney Lysate at 10 µg

    Predicted band size : 36 kDa

References for Anti-Glutamyl hydrolase gamma antibody (ab125473)

ab125473 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125473.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"