Anti-Glutathione Peroxidase 4 antibody (ab116703)

Overview

  • Product name
    Anti-Glutathione Peroxidase 4 antibody
    See all Glutathione Peroxidase 4 primary antibodies
  • Description
    Goat polyclonal to Glutathione Peroxidase 4
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    EEPLVIEKDLPHY

    with a Cysteine residue linker, corresponding to C terminal amino acids 184-196 of Human Glutathione Peroxidase 4 (NP_002076.2).

  • Positive control
    • Human Testis lysate and tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab116703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 22 kDa.
ELISA 1/16000.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
  • Tissue specificity
    Present primarily in testis.
  • Sequence similarities
    Belongs to the glutathione peroxidase family.
  • Cellular localization
    Mitochondrion. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glutathione peroxidase 4 antibody
    • GPX 4 antibody
    • GPX-4 antibody
    • GPX4 antibody
    • GPX4_HUMAN antibody
    • GSHPx-4 antibody
    • MCSP antibody
    • mitochondrial antibody
    • PHGPx antibody
    • Phospholipid hydroperoxidase antibody
    • Phospholipid hydroperoxide glutathione peroxidase antibody
    • Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody
    • snGPx antibody
    • snPHGPx antibody
    • Sperm nucleus glutathione peroxidase antibody
    see all

Images

  • Anti-Glutathione Peroxidase 4 antibody (ab116703) at 0.1 µg/ml + Human Testis lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 22 kDa
  • ab116703, at 2.5 µg/ml, staining Glutathione Peroxidase 4 in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab116703 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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