The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 22 kDa.
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
FunctionProtects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
Tissue specificityPresent primarily in testis.
Sequence similaritiesBelongs to the glutathione peroxidase family.
ab116703, at 2.5 µg/ml, staining Glutathione Peroxidase 4 in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
References for Anti-Glutathione Peroxidase 4 antibody (ab116703)
has not yet been referenced specifically in any publications.
Publishing research using ab116703? Please let us know so that we can cite the reference in this datasheet.
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