Anti-Glycerol kinase antibody (HRP) (ab181643)

Overview

  • Product name
    Anti-Glycerol kinase antibody (HRP)
    See all Glycerol kinase primary antibodies
  • Description
    Goat polyclonal to Glycerol kinase (HRP)
  • Conjugation
    HRP
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Immunogen

    Full length native protein (purified) corresponding to Glycerol kinase. (Cellulomonas species).

Properties

Applications

Our Abpromise guarantee covers the use of ab181643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 55 kDa.
ELISA 1/4000 - 1/20000.

ab181643 has been assayed against 1.0 ug of Glycerol Kinase [Cellulomonas species] in a standard capture ELISA using ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) as a substrate for 30 minutes at room temperature.

Target

  • Function
    Key enzyme in the regulation of glycerol uptake and metabolism.
  • Tissue specificity
    Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
  • Pathway
    Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
  • Involvement in disease
    Defects in GK are the cause of GK deficiency (GKD) [MIM:307030]. This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only.
  • Sequence similarities
    Belongs to the FGGY kinase family.
  • Cellular localization
    Mitochondrion outer membrane. Cytoplasm. In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.
  • Information by UniProt
  • Alternative names
    • ATP glycerol 3 phosphotransferase antibody
    • ATP:glycerol 3 phosphotransferase antibody
    • ATP:glycerol 3-phosphotransferase antibody
    • D930012N15Rik antibody
    • GK antibody
    • GK1 antibody
    • GKD antibody
    • GLPK_HUMAN antibody
    • Glycerokinase antibody
    • Glycerol kinase antibody
    • OTTHUMP00000023108 antibody
    • OTTHUMP00000023109 antibody
    • OTTHUMP00000215321 antibody
    see all

References

ab181643 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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