Anti-Glycogen synthase 1 antibody (ab123377)

Overview

  • Product name
    Anti-Glycogen synthase 1 antibody
    See all Glycogen synthase 1 primary antibodies
  • Description
    Rabbit polyclonal to Glycogen synthase 1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    PSPSL

    , corresponding to a region around amino acids 644-648 of Human Glycogen synthase 1 (P13807 ).

  • Positive control
    • HeLa and 293 cell extracts

Properties

Applications

Our Abpromise guarantee covers the use of ab123377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 84 kDa (predicted molecular weight: 84 kDa). Incubate membrane with diluted antibody in 5% nonfat milk, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking over night.

Target

  • Function
    Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
  • Pathway
    Glycan biosynthesis; glycogen biosynthesis.
  • Involvement in disease
    Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.
  • Sequence similarities
    Belongs to the glycosyltransferase 3 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glycogen [starch] synthase antibody
    • Glycogen synthase 1 (muscle) antibody
    • Glycogen synthase 1 antibody
    • GSY antibody
    • GYS antibody
    • Gys1 antibody
    • GYS1_HUMAN antibody
    • muscle antibody
    see all

Images

  • All lanes : Anti-Glycogen synthase 1 antibody (ab123377) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : 293 cell extract


    Predicted band size : 84 kDa

References

ab123377 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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