Anti-Glycogen synthase 1 (phospho S645) antibody (ab53691)


  • Product nameAnti-Glycogen synthase 1 (phospho S645) antibody
    See all Glycogen synthase 1 primary antibodies
  • Description
    Rabbit polyclonal to Glycogen synthase 1 (phospho S645)
  • Specificityab53691 detects endogenous levels of Glycogen Synthase only when phosphorylated at serine 645.
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic phosphopeptide derived from human Glycogen Synthase around the phosphorylation site of serine 645 (P-P-SP-P-S).

  • Positive control
    • Human skeletal muscle tissue.



Our Abpromise guarantee covers the use of ab53691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
IHC-P 1/5.


  • FunctionTransfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
  • PathwayGlycan biosynthesis; glycogen biosynthesis.
  • Involvement in diseaseDefects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.
  • Sequence similaritiesBelongs to the glycosyltransferase 3 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glycogen [starch] synthase antibody
    • Glycogen synthase 1 (muscle) antibody
    • Glycogen synthase 1 antibody
    • GSY antibody
    • GYS antibody
    • Gys1 antibody
    • GYS1_HUMAN antibody
    • muscle antibody
    see all

Anti-Glycogen synthase 1 (phospho S645) antibody images

  • ab53691 at 1/50 dilution staining Glycogen Synthase 1 in human skeletal muscle by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.
  • IHC image of ab53691 staining in human normal skeletal muscle formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab53691, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

References for Anti-Glycogen synthase 1 (phospho S645) antibody (ab53691)

ab53691 has not yet been referenced specifically in any publications.

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