Overview

  • Product nameAnti-Glycogenin 1 antibody
    See all Glycogenin 1 primary antibodies
  • Description
    Rabbit polyclonal to Glycogenin 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 284-333 (SDLSFGEAPA APQPSMSSEE RKERWEQGQA DYMGADSFDN IKRKLDTYLQ) of Mouse Glycogenin 1 (NM_013755).

  • Positive control
    • Mouse kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab111711 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSelf-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.
  • PathwayGlycan biosynthesis; glycogen biosynthesis.
  • Involvement in diseaseDefects in GYG1 are the cause of glycogen storage disease type 15 (GSD15) [MIM:613507]. It is a metabolic disorder resulting in muscle weakness, associated with the glycogen depletion in skeletal muscle, and cardiac arrhythmia, associated with the accumulation of abnormal storage material in the heart. The skeletal muscle shows a marked predominance of slow-twitch, oxidative muscle fibers and mitochondrial proliferation.
  • Sequence similaritiesBelongs to the glycogenin family.
  • Post-translational
    modifications
    Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195.
    Phosphorylated.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glycogenin antibody
    • Glycogenin-1 antibody
    • Glycogenin1 antibody
    • GLYG_HUMAN antibody
    • GN-1 antibody
    • GN1 antibody
    • GYG 1 antibody
    • GYG antibody
    • GYG1 antibody
    see all

Anti-Glycogenin 1 antibody images

  • Anti-Glycogenin 1 antibody (ab111711) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 37 kDa

References for Anti-Glycogenin 1 antibody (ab111711)

ab111711 has not yet been referenced specifically in any publications.

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