Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab55221 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 39 kDa.
IHC-P Use a concentration of 3 µg/ml.

Target

  • FunctionSelf-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.
  • PathwayGlycan biosynthesis; glycogen biosynthesis.
  • Involvement in diseaseDefects in GYG1 are the cause of glycogen storage disease type 15 (GSD15) [MIM:613507]. It is a metabolic disorder resulting in muscle weakness, associated with the glycogen depletion in skeletal muscle, and cardiac arrhythmia, associated with the accumulation of abnormal storage material in the heart. The skeletal muscle shows a marked predominance of slow-twitch, oxidative muscle fibers and mitochondrial proliferation.
  • Sequence similaritiesBelongs to the glycogenin family.
  • Post-translational
    modifications
    Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195.
    Phosphorylated.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glycogenin antibody
    • Glycogenin-1 antibody
    • Glycogenin1 antibody
    • GLYG_HUMAN antibody
    • GN-1 antibody
    • GN1 antibody
    • GYG 1 antibody
    • GYG antibody
    • GYG1 antibody
    see all

Anti-Glycogenin 1 antibody images



  • Predicted band size : 39 kDa
    Glycogenin 1 antibody (ab55221) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
  • ab55221 at 3 µg/ml staining Glycogenin 1 in human testis tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).

References for Anti-Glycogenin 1 antibody (ab55221)

ab55221 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"