Overview

  • Product nameAnti-GMP Synthase antibody
    See all GMP Synthase primary antibodies
  • Description
    Mouse monoclonal to GMP Synthase
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 108-216 of Human GMP Synthase

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 µg/ml.
WB Use a concentration of 1 - 5 µg/ml.

Target

  • FunctionInvolved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
  • PathwayPurine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
  • Involvement in diseaseNote=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with MLL.
  • Sequence similaritiesContains 1 glutamine amidotransferase type-1 domain.
    Contains 1 GMP-binding domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glutamine amidotransferase antibody
    • GMP synthase [glutamine hydrolyzing] antibody
    • GMP synthase [glutamine-hydrolyzing] antibody
    • GMP synthetase antibody
    • Gmps antibody
    • GUAA_HUMAN antibody
    • Guanine monphosphate synthetase antibody
    • Guanosine 5' monophosphate synthase antibody
    • MLL/GMPS fusion protein antibody
    see all

Anti-GMP Synthase antibody images

  • GMP Synthase antibody (ab56530) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.
  • Western blot against tagged recombinant protein immunogen using ab56530 GMP Synthase antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

References for Anti-GMP Synthase antibody (ab56530)

ab56530 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"