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Rabbit polyclonal to GNAL
Predicted to work with:
Synthetic peptide corresponding to Human GNAL aa 60-90 (internal sequence).
Human brain tissue. Extracts from LOVO cells.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 44 kDa.
1/50 - 1/100.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
Belongs to the G-alpha family. G(s) subfamily.
Information by UniProt
Adenylate cyclase stimulating G alpha protein, olfactory type antibody
Adenylate cyclase-stimulating G alpha protein antibody
Western blot - Anti-GNAL antibody (ab74049)
All lanes : Anti-GNAL antibody (ab74049) at 1/500 dilution Lane 1 : extracts from LOVO cells Lane 2 : extracts from LOVO cells with immunizing peptide at 10 µg Lysates/proteins at 30 µg per lane. Predicted band size: 44 kDa Observed band size: 44 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GNAL antibody (ab74049)
Immunohistochemistry analysis of paraffin-embedded
human brain tissue using 1/50 ab74049, in the absence (left) or presence (right) of the immunizing peptide.
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