• Product name
  • Description
    Rabbit polyclonal to GNAL
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human GNAL aa 60-90 (internal sequence).

  • Positive control
    • Human brain tissue. Extracts from LOVO cells.



Our Abpromise guarantee covers the use of ab74049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
ELISA 1/20000.
IHC-P 1/50 - 1/100.


  • Function
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
  • Tissue specificity
    Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
  • Sequence similarities
    Belongs to the G-alpha family. G(s) subfamily.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adenylate cyclase stimulating G alpha protein, olfactory type antibody
    • Adenylate cyclase-stimulating G alpha protein antibody
    • DYT25 antibody
    • G alpha olf antibody
    • Gnal antibody
    • GNAL_HUMAN antibody
    • Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type antibody
    • Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type antibody
    • Guanine nucleotide binding protein G(olf) subunit alpha antibody
    • Guanine nucleotide-binding protein G(olf) subunit alpha antibody
    • olfactory type antibody
    see all

Anti-GNAL antibody images

  • All lanes : Anti-GNAL antibody (ab74049) at 1/500 dilution

    Lane 1 : extracts from LOVO cells
    Lane 2 : extracts from LOVO cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 44 kDa
    Observed band size : 44 kDa
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue using 1/50 ab74049, in the absence (left) or presence (right) of the immunizing peptide.

References for Anti-GNAL antibody (ab74049)

This product has been referenced in:
  • Zhang L  et al. Dopamine receptor and Ga(olf) expression in DYT1 dystonia mouse models during postnatal development. PLoS One 10:e0123104 (2015). WB . Read more (PubMed: 25860259) »
  • Griffin CA  et al. MOR23 promotes muscle regeneration and regulates cell adhesion and migration. Dev Cell 17:649-61 (2009). WB ; Mouse . Read more (PubMed: 19922870) »

See all 2 Publications for this product

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