Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Rod. Predominantly expressed in the retina followed by the ciliary body, iris and retinal pigment epithelium.
Involvement in disease
Night blindness, congenital stationary, autosomal dominant 3 Night blindness, congenital stationary, 1C
Belongs to the G-alpha family. G(i/o/t/z) subfamily.