Overview

  • Product name
    GNAT1 peptide

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab5002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human Tr alpha, catalog ab3504. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • CSNBAD3
    • GBT1
    • GNAT1
    • GNAT1_HUMAN
    • GNATR
    • guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1
    • guanine nucleotide binding protein G(T) alpha 1 subunit
    • Guanine nucleotide-binding protein G(t) subunit alpha-1
    • Rod specific transducin
    • rod-type transducin alpha subunit
    • Transducin alpha-1 chain
    • transducin, rod-specific
    see all
  • Function
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
  • Tissue specificity
    Rod. Predominantly expressed in the retina followed by the ciliary body, iris and retinal pigment epithelium.
  • Involvement in disease
    Night blindness, congenital stationary, autosomal dominant 3
    Night blindness, congenital stationary, 1C
  • Sequence similarities
    Belongs to the G-alpha family. G(i/o/t/z) subfamily.
  • Developmental stage
    Expressed at approximately postnatal day 7.
  • Information by UniProt

References

ab5002 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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