For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to GNPAT
ab75060 detects endogenous levels of total GNPAT protein.
Synthetic peptide derived from C-terminal region of human GNPAT.
Extracts from HT-29 cells and RAW264.7cells
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
ab75060 was purified using an epitope-specific immunogen.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 77 kDa.
Membrane lipid metabolism; glycerophospholipid metabolism.
Involvement in disease
Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2) [MIM:222765]. RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
Belongs to the GPAT/DAPAT family.
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
Peroxisome membrane. Exclusively localized to the lumenal side of the peroxisomal membrane.
Information by UniProt
Acyl CoA dihydroxyacetonephosphateacyltransferase antibody
DAP AT antibody
Anti-GNPAT antibody images
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"