Overview

  • Product nameAnti-GOLGA5 antibody
    See all GOLGA5 primary antibodies
  • Description
    Mouse monoclonal to GOLGA5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: SWFVDLAGKA EDLLNRVDQG AATALSRKDN ASNIYSKNTD YTELHQQNTD LIYQTGPKST YISSAADNIR NQKATILAGT ANVKVGSRTP VEASHPVE, corresponding to amino acids 2-100 of Human GOLGA5

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56895 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
    • Tissue specificityUbiquitous. Highly expressed in seminiferous tubules and Leydig cells in testis, and detected at much lower levels in the other tissues tested. Expression is very low or not detectable in spermatozoa.
    • Involvement in diseaseDefects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving GOLGA5 is found in thyroid papillary carcinomas. Translocation t(10;14)(q11;q32) with RET. The translocation generates the RET/GOLGA5 (PTC5) oncogene which was found in 2 cases of PACT in children exposed to radioactive fallout after Chernobyl.
    • Post-translational
      modifications
      Highly phosphorylated during mitosis. Phosphorylation is barely detectable during interphase.
    • Cellular localizationGolgi apparatus membrane. Found throughout the Golgi, both on cisternae and, at higher abundance, on the tubulo-vesicular structures of the cis-Golgi network.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cell proliferation inducing gene 31 antibody
      • Cell proliferation-inducing gene 31 protein antibody
      • GOGA5_HUMAN antibody
      • GOLGA 5 antibody
      • GOLGA5 antibody
      • Golgi autoantigen golgin subfamily a 5 antibody
      • Golgi integral membrane protein 5 antibody
      • Golgin 84 antibody
      • Golgin A5 antibody
      • Golgin subfamily A member 5 antibody
      • Golgin-84 antibody
      • Golgin84 antibody
      • GOLIM 5 antibody
      • GOLIM5 antibody
      • Protein Ret-II antibody
      • PTC5 antibody
      • Ret fused gene 5 antibody
      • RET fused gene 5 protein antibody
      • Ret II antibody
      • Ret II protein antibody
      • RET-fused gene 5 protein antibody
      • RFG 5 antibody
      • RFG5 antibody
      see all

    Anti-GOLGA5 antibody images



    • Predicted band size : 83 kDa
      GOLGA5 antibody (ab56895) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    References for Anti-GOLGA5 antibody (ab56895)

    ab56895 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab56895.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"