Overview

  • Product nameAnti-GOLPH2 antibody
    See all GOLPH2 primary antibodies
  • Description
    Rabbit polyclonal to GOLPH2
  • Specificityab92612 will not recognize GOLPH1 or GOLPH3.
  • Tested applicationsSuitable for: ICC/IF, WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic 18 amino acid peptide from near the center of Human GOLPH2 (GenBank accession no. EAW62705).

  • Positive control
    • Rat brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab92612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 45 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionUnknown. Cellular response protein to viral infection.
  • Tissue specificityWidely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocyte-derived syncitial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
  • Sequence similaritiesBelongs to the GOLM1/CASC4 family.
  • Post-translational
    modifications
    Glycosylated.
    Phosphorylation sites are present in the extracelllular medium.
  • Cellular localizationGolgi apparatus > cis-Golgi network membrane. Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA379P1.3 antibody
    • C9orf155 antibody
    • Chromosome 9 open reading frame 155 antibody
    • Golgi membrane protein 1 antibody
    • Golgi membrane protein GP73 antibody
    • Golgi phosphoprotein 2 antibody
    • Golgi protein 73 kD antibody
    • Golgi protein 73kD antibody
    • GOLM 1 antibody
    • GOLM1 antibody
    • GOLM1_HUMAN antibody
    • GOLPH 2 antibody
    • GOLPH2 antibody
    • GP 73 antibody
    • GP73 antibody
    • PSEC0257 antibody
    see all

Anti-GOLPH2 antibody images

  • Immunofluorescence of GOLPH2 in rat brain tissue with ab92612 at 20 ug/mL.

  • Immunohistochemistry of rat brain tissue with ab92612 at 2.5 μg/mL.

  • Lane 1 : Anti-GOLPH2 antibody (ab92612) at 0.25 µg/ml
    Lane 2 : Anti-GOLPH2 antibody (ab92612) at 0.5 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 45 kDa

References for Anti-GOLPH2 antibody (ab92612)

ab92612 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"