• Product name
    Anti-GOT2 antibody [EPR12354(B)]
    See all GOT2 primary antibodies
  • Description
    Rabbit monoclonal [EPR12354(B)] to GOT2
  • Host species
  • Tested applications
    Suitable for: WB, IHC-P, IP, Flow Cytmore details
    Unsuitable for: ICC/IF
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GOT2 aa 1-100 (Cysteine residue). The exact sequence is proprietary.
    Database link: P00505

  • Positive control
    • Human fetal liver lysate; 293T, HepG2 and HeLa cell lysate; Human liver and urinary bladder carcinoma tissue; permeabilized 293T cells.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents



Our Abpromise guarantee covers the use of ab171739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
IHC-P 1/50 - 1/100.
IP 1/10 - 1/100.
Flow Cyt 1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • Application notes
    Is unsuitable for ICC/IF.
  • Target

    • Function
      Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
    • Sequence similarities
      Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
    • Cellular localization
      Mitochondrion matrix. Cell membrane. Exposure to alcohol promotes translocation to the cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AATM_HUMAN antibody
      • AL022787 antibody
      • Aspartate aminotransferase 2 antibody
      • Aspartate aminotransferase antibody
      • Aspartate aminotransferase, mitochondrial antibody
      • Aspartate transaminase 2 antibody
      • ASPATA antibody
      • EC antibody
      • FABP 1 antibody
      • FABP pm antibody
      • FABP-1 antibody
      • FABPpm antibody
      • Fatty acid binding protein antibody
      • Fatty acid-binding protein antibody
      • FLJ40994 antibody
      • Glutamate oxaloacetate transaminase 2 antibody
      • Glutamate oxaloacetate transaminase 2, mitochondrial antibody
      • Glutamate oxaloacetate transaminase, mitochondrial antibody
      • Glutamic oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) antibody
      • Got 2 antibody
      • GOT2 antibody
      • KAT4 antibody
      • KATIV antibody
      • kynurenine aminotransferase 4 antibody
      • Kynurenine aminotransferase IV antibody
      • kynurenine--oxoglutarate transaminase 4 antibody
      • kynurenine--oxoglutarate transaminase IV antibody
      • mAspAT antibody
      • MGC102129 antibody
      • MGC115763 antibody
      • mitAAT antibody
      • mitochondrial antibody
      • Mitochondrial aspartate aminotransferase antibody
      • OTTMUSP00000017748 antibody
      • Plasma membrane fatty acid binding protein antibody
      • Plasma membrane-associated fatty acid-binding protein antibody
      • Transaminase A antibody
      see all


    • Flow cytometric analysis of permeabilized 293T cells labeling GOT2 using ab171739 at 1/100 (red) or a rabbit IgG (negative) (green).

    • Immunohistochemistry of paraffin-embedded Human urinary bladder carcinoma tissue labeling GOT2 using ab171739 at 1/50 dilution.

    • Immunohistochemistry of paraffin-embedded Human liver tissue labeling GOT2 using ab171739 at 1/50 dilution.

    • Western blot analysis on immunoprecipitation pellet from Human fetal liver lysate (lane 1) labeling GOT2 using ab171739 at 1/10 dilution, and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG. Lane 2: 1X PBS (negative control).

    • All lanes : Anti-GOT2 antibody [EPR12354(B)] (ab171739) at 1/1000 dilution

      Lane 1 : Human fetal liver lysate
      Lane 2 : 293T cell lysate
      Lane 3 : HepG2 cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 48 kDa


    This product has been referenced in:
    • Schatton D  et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-693 (2017). WB ; Mouse . Read more (PubMed: 28188211) »
    • Gao J  et al. CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins. J Cell Biol 207:213-23 (2014). Read more (PubMed: 25349259) »

    See all 2 Publications for this product

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