Overview

  • Product name
    Anti-GPAT-2 antibody
  • Description
    Rabbit polyclonal to GPAT-2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: HQKGVFLSQL LGEFSWLTEE ILLRGFDVGF SGQLRSLLQH SLSLLRAHVA LLRIRQGDLL VVPQPGPGLT HLA, corresponding to amino acids 474-540 of Human GPAT-2 (UniProt ID: Q6NUI2).

  • Positive control
    • Human pancreas tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab122373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
  • Pathway
    Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
  • Sequence similarities
    Belongs to the GPAT/DAPAT family.
  • Domain
    The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
  • Cellular localization
    Mitochondrion outer membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glycerol-3-phosphate acyltransferase 2 antibody
    • GPAT-2 antibody
    • GPAT2 antibody
    • GPAT2_HUMAN antibody
    • mitochondrial antibody
    • xGPAT1 antibody
    see all

Images

  • ab122373, at a 1/50 dilution, staining GPAT-2 in paraffin embedded Human pancreas tissue by Immunohistochemistry.

References

ab122373 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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