Anti-GPBB antibody (ab154969)
Key features and details
- Rabbit polyclonal to GPBB
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-GPBB antibody
See all GPBB primary antibodies -
Description
Rabbit polyclonal to GPBB -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Chicken -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 519-813 of Human GPBB (UniProt P11216).
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Positive control
- 293T, A431, H1299, HeLaS3, HepG2, MOLT4, Raji and Mouse brain lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154969 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 96 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 96 kDa. |
Target
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Function
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. -
Sequence similarities
Belongs to the glycogen phosphorylase family. -
Post-translational
modificationsPhosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A. - Information by UniProt
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Database links
- Entrez Gene: 421248 Chicken
- Entrez Gene: 5834 Human
- Entrez Gene: 110078 Mouse
- Entrez Gene: 25739 Rat
- Omim: 138550 Human
- SwissProt: P11216 Human
- SwissProt: Q8CI94 Mouse
- SwissProt: P53534 Rat
see all -
Alternative names
- Brain glycogen phosphorylase antibody
- Glycogen phosphorylase B antibody
- Glycogen phosphorylase brain form antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab154969 has been referenced in 5 publications.
- Jiang L et al. Analysis of the expression, function and signaling of glycogen phosphorylase isoforms in hepatocellular carcinoma. Oncol Lett 24:244 (2022). PubMed: 35761940
- Liu C et al. Glycogen Phosphorylase: A Drug Target of Amino Alcohols in Echinococcus granulosus, Predicted by a Computer-Aided Method. Front Microbiol 11:557039 (2020). PubMed: 33329421
- Fan Z et al. Dynamic Variations in Brain Glycogen are Involved in Modulating Isoflurane Anesthesia in Mice. Neurosci Bull 36:1513-1523 (2020). PubMed: 33048310
- Zhang S et al. PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines. Mol Med Rep 18:715-722 (2018). PubMed: 29845265
- Wang Z et al. Silencing of PYGB suppresses growth and promotes the apoptosis of prostate cancer cells via the NF-?B/Nrf2 signaling pathway. Mol Med Rep 18:3800-3808 (2018). PubMed: 30106110