Overview

  • Product nameAnti-GPCR GPR124 antibody
    See all GPCR GPR124 primary antibodies
  • Description
    Rabbit polyclonal to GPCR GPR124
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide (Human) of 15 amino acids in length, near the C terminus

  • Positive control
    • Human Bladder Tissue Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 142 kDa).
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • FunctionEndothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
  • Tissue specificityExpressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • DomainBinds to DLG1 through its PDZ-binding motif.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp434C211 antibody
    • DKFZp434J0911 antibody
    • FLJ14390 antibody
    • G protein coupled receptor 124 antibody
    • G-protein coupled receptor 124 antibody
    • GP124_HUMAN antibody
    • GPR 124 antibody
    • Gpr124 antibody
    • KIAA1531 antibody
    • TEM 5 antibody
    • TEM5 antibody
    • Tumor endothelial marker 5 antibody
    • Tumor endothelial marker 5 precursor antibody
    see all

Anti-GPCR GPR124 antibody images

  • Lane 1 : Anti-GPCR GPR124 antibody (ab67279) at 2 µg/ml
    Lane 2 : Anti-GPCR GPR124 antibody (ab67279) at 4 µg/ml

    Lane 1 : Human bladder tissue lysate
    Lane 2 : Human bladder tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 142 kDa
    Observed band size : 180 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 95 kDa. We are unsure as to the identity of these extra bands.
  • ab67279 at 2.5µg/ml staining of GPCR GPR124 in human bladder tissue using IHC-P.

References for Anti-GPCR GPR124 antibody (ab67279)

ab67279 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab67279.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"