Overview

  • Product nameAnti-GPCR GPR124 antibody
    See all GPCR GPR124 primary antibodies
  • Description
    Rabbit polyclonal to GPCR GPR124
  • Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide (Human) of 14 amino acids from the central region

  • Positive control
    • Rat Kidney Tissue Lysate Human bladder tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab67280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 142 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionEndothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
  • Tissue specificityExpressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • DomainBinds to DLG1 through its PDZ-binding motif.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp434C211 antibody
    • DKFZp434J0911 antibody
    • FLJ14390 antibody
    • G protein coupled receptor 124 antibody
    • G-protein coupled receptor 124 antibody
    • GP124_HUMAN antibody
    • GPR 124 antibody
    • Gpr124 antibody
    • KIAA1531 antibody
    • TEM 5 antibody
    • TEM5 antibody
    • Tumor endothelial marker 5 antibody
    • Tumor endothelial marker 5 precursor antibody
    see all

Anti-GPCR GPR124 antibody images

  • Immunofluorescence of GPCR GPR124 in Human bladder tissue with ab67280 at 20 ug/mL.

  • Lane 1 : Anti-GPCR GPR124 antibody (ab67280) at 2 µg/ml
    Lane 2 : Anti-GPCR GPR124 antibody (ab67280) at 4 µg/ml

    Lane 1 : Rat kidney tissue lysate
    Lane 2 : Rat kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 142 kDa
    Observed band size : 176,180 kDa (why is the actual band size different from the predicted?)
  • ab67280 at 5µg/ml staining of  GPCR GPR124 in human bladder tissue using IHC-P.

References for Anti-GPCR GPR124 antibody (ab67280)

ab67280 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"