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Rabbit polyclonal to GPCR GPR126 - C-terminal
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted to work with:
Gorilla, Common marmoset
Synthetic peptide within Human GPCR GPR126 (C terminal). The exact sequence is proprietary. 16 amino acid peptide.
Database link: Q86SQ4
Human brain, neurons and glia tissue.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Orphan receptor. May be required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels.
Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 CUB domain. Contains 1 GPS domain. Contains 1 pentaxin domain.
Proteolytically cleaved into 2 conserved sites: one in the GPS domain (S1 site) and the other in the middle of the extracellular domain (S2 site). The proteolytic cleavage at S1 site generates an extracellular subunit and a seven-transmembrane subunit. Furin is involved in the cleavage of the S2 site generating a soluble fragment. Processing at the GPS domain occurred independent of and probably prior to the cleavage at the S2 site.
Cell membrane. Detected on the cell surface of activated but not resting umbilical vein.
Information by UniProt
adhesion G protein coupled receptor G6 antibody
Developmentally regulated G protein coupled receptor antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR126 antibody - C-terminal (ab188895)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons and glia tissue labeling GPCR GPR126 with ab188895 at 5 µg/ml.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"