Overview

  • Product nameGPCR GPR15 peptide

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab6101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Blocking

  • FormLiquid
  • Additional notesStable for one year.


    Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein coupled receptors, including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively) were recently cloned. This novel G protein coupled receptor serves as co-receptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • BOB
    • Brother of Bonzo
    • G protein coupled receptor 15
    • G protein coupled receptor GPR15
    • G-protein coupled receptor 15
    • GPR15
    • GPR15_HUMAN
    see all
  • FunctionProbable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for GPCR GPR15 peptide (ab6101)

ab6101 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry regarding ab6101 GPR15 (N-term) peptide. As far as I we are aware the only tested application for this antibody is blocking. All other information we have available pertaining this antibody is accesible on the online datashee...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"