Overview

  • Product name
  • Description
    Rabbit polyclonal to GPCR GPR17
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 237-266 of Human GPCR GPR17.

  • Positive control
    • MDA-MB435 cell line lysates. Brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab103480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
  • Tissue specificity
    Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686M18273 antibody
    • G protein coupled receptor 17 antibody
    • G-protein coupled receptor 17 antibody
    • GPR 17 antibody
    • Gpr17 antibody
    • GPR17_HUMAN antibody
    • P2Y like receptor antibody
    • P2Y-like receptor antibody
    • Probable P2Y purinoceptor GPR 17 antibody
    • Probable P2Y purinoceptor GPR17 antibody
    • R12 antibody
    • UDP/CysLT receptor antibody
    • Uracil nucleotide/cysteinyl leukotriene receptor antibody
    see all

Images

  • Anti-GPCR GPR17 antibody (ab103480) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa
  • ab103480 at 1/50 dilution staining GPCR GPR17 in formalin-fixed and paraffin-embedded brain tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

References

ab103480 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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