The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).
FunctionDual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
Tissue specificityExpressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.