Overview

  • Product nameAnti-GPCR GPR17 antibody
    See all GPCR GPR17 primary antibodies
  • Description
    Goat polyclonal to GPCR GPR17
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    C-EGKTNESSLSAKSE

    , corresponding to C terminal amino acids 353-366 of Human GPCR GPR17 (NP_005282.1).

  • Positive control
    • Human cerebellum lysate; Mouse and Rat brain lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).

Target

  • FunctionDual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
  • Tissue specificityExpressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686M18273 antibody
    • G protein coupled receptor 17 antibody
    • G-protein coupled receptor 17 antibody
    • GPR 17 antibody
    • Gpr17 antibody
    • GPR17_HUMAN antibody
    • P2Y like receptor antibody
    • P2Y-like receptor antibody
    • Probable P2Y purinoceptor GPR 17 antibody
    • Probable P2Y purinoceptor GPR17 antibody
    • R12 antibody
    • UDP/CysLT receptor antibody
    • Uracil nucleotide/cysteinyl leukotriene receptor antibody
    see all

Anti-GPCR GPR17 antibody images

  • Anti-GPCR GPR17 antibody (ab106781) at 0.3 µg/ml + Rat brain lysates at 35 µg

    Predicted band size : 41 kDa
  • Anti-GPCR GPR17 antibody (ab106781) at 0.1 µg/ml + Human brain (cerebellum) lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa
    Observed band size : 45 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

References for Anti-GPCR GPR17 antibody (ab106781)

ab106781 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106781.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"