Overview

  • Product name
  • Description
    Goat polyclonal to GPCR GPR17
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    C-EGKTNESSLSAKSE

    , corresponding to C terminal amino acids 353-366 of Human GPCR GPR17 (NP_005282.1).

  • Positive control
    • Human cerebellum lysate; Mouse and Rat brain lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).

Target

  • Function
    Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
  • Tissue specificity
    Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686M18273 antibody
    • G protein coupled receptor 17 antibody
    • G-protein coupled receptor 17 antibody
    • GPR 17 antibody
    • Gpr17 antibody
    • GPR17_HUMAN antibody
    • P2Y like receptor antibody
    • P2Y-like receptor antibody
    • Probable P2Y purinoceptor GPR 17 antibody
    • Probable P2Y purinoceptor GPR17 antibody
    • R12 antibody
    • UDP/CysLT receptor antibody
    • Uracil nucleotide/cysteinyl leukotriene receptor antibody
    see all

Images

  • Anti-GPCR GPR17 antibody (ab106781) at 0.3 µg/ml + Rat brain lysates at 35 µg

    Predicted band size : 41 kDa
  • Anti-GPCR GPR17 antibody (ab106781) at 0.1 µg/ml + Human brain (cerebellum) lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa
    Observed band size : 45 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

References

ab106781 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab106781.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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