Overview

  • Product name
  • Description
    Rabbit polyclonal to GPCR GPR17
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Chinese hamster
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 200 - 300 of Rat GPCR GPR17.

  • Positive control
    • This antibody gave a positive signal in the following tissue lysates: Rat Kidney; Mouse Kidney.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 38 kDa).

Target

  • Function
    Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
  • Tissue specificity
    Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686M18273 antibody
    • G protein coupled receptor 17 antibody
    • G-protein coupled receptor 17 antibody
    • GPR 17 antibody
    • Gpr17 antibody
    • GPR17_HUMAN antibody
    • P2Y like receptor antibody
    • P2Y-like receptor antibody
    • Probable P2Y purinoceptor GPR 17 antibody
    • Probable P2Y purinoceptor GPR17 antibody
    • R12 antibody
    • UDP/CysLT receptor antibody
    • Uracil nucleotide/cysteinyl leukotriene receptor antibody
    see all

Images

  • All lanes : Anti-GPCR GPR17 antibody (ab111472) at 1 µg/ml

    Lane 1 : Kidney (Rat) Tissue Lysate
    Lane 2 : Kidney (Mouse) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 38 kDa
    Observed band size : 41 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 14 kDa,31 kDa,74 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 3 minutes

References

ab111472 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab111472.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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