Overview

  • Product name
  • Description
    Rabbit polyclonal to GPCR GPR20
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region from N-terminal extracellular domain of Human GPCR GPR20.

  • Positive control
    • Human Basal Nucleus of Meynert tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab117082 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
  • Tissue specificity
    Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor 20 antibody
    • G-protein coupled receptor 20 antibody
    • Gpr20 antibody
    • GPR20_HUMAN antibody

Images

  • Human Basal Nucleus of Meynert (formalin-fixed, paraffin-embedded) stained with ab117082 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab117082 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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