Recombinant
RabMAb

Anti-GPCR GPR37 antibody [EPR10728] (ab166614)

Overview

  • Product name
    Anti-GPCR GPR37 antibody [EPR10728]
    See all GPCR GPR37 primary antibodies
  • Description
    Rabbit monoclonal [EPR10728] to GPCR GPR37
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human GPCR GPR37 aa 50-150. The exact sequence is proprietary.

  • Positive control
    • fetal brain lysate
  • General notes

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR10728
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab166614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Orphan receptor. May have a unique functional role in the central nervous system.
    • Tissue specificity
      Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family.
    • Post-translational
      modifications
      Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.
    • Cellular localization
      Cell membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • EDNRBL antibody
      • Endothelin B receptor like protein 1 antibody
      • Endothelin B receptor-like protein 1 antibody
      • Endothelin receptor type B like antibody
      • ETBR LP 1 antibody
      • ETBR-LP-1 antibody
      • ETBRLP1 antibody
      • G protein coupled receptor 37 antibody
      • G protein coupled receptor 37 endothelin receptor type B like antibody
      • Gpr37 antibody
      • GPR37_HUMAN antibody
      • hET(B)R LP antibody
      • hET(B)RLP antibody
      • PAELR antibody
      • Parkin associated endothelin receptor like receptor antibody
      • Parkin-associated endothelin receptor-like receptor antibody
      • Probable G protein coupled receptor 37 antibody
      • Probable G-protein coupled receptor 37 antibody
      see all

    Images

    • Anti-GPCR GPR37 antibody [EPR10728] (ab166614) at 1/1000 dilution + fetal brain lysate
      at 10 µg/ml

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 67 kDa
      Observed band size: 67 kDa

    References

    ab166614 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab166614.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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