Anti-GPCR GPR40 antibody - C-terminal (ab188920)

Overview

  • Product name
    Anti-GPCR GPR40 antibody - C-terminal
    See all GPCR GPR40 primary antibodies
  • Description
    Rabbit polyclonal to GPCR GPR40 - C-terminal
  • Host species
    Rabbit
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human GPCR GPR40 (C terminal). NP_005294.1.
    Database link: O14842

  • Positive control
    • Human brain, neurons tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab188920 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 32 kDa.
IHC-P Use a concentration of 9 - 18 µg/ml.

Target

  • Function
    Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.
  • Tissue specificity
    Expressed abundantly in pancreatic beta cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FFA1R antibody
    • FFAR 1 antibody
    • Ffar1 antibody
    • FFAR1_HUMAN antibody
    • Free fatty acid receptor 1 antibody
    • G protein coupled receptor 40 antibody
    • G-protein coupled receptor 40 antibody
    • GPCR40 antibody
    • GPR 40 antibody
    • GPR40 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons tissue labeling GPCR GPR40 with ab188920 at 9 µg/ml.

References

ab188920 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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