Overview

  • Product name
    GPCR GPR40 peptide (289-300)

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      CAARTQGGKSQK
    • Amino acids
      289 to 300

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45737 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-GPCR GPR40 antibody (ab32889)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • FFA1R
    • FFAR 1
    • Ffar1
    • FFAR1_HUMAN
    • Free fatty acid receptor 1
    • G protein coupled receptor 40
    • G-protein coupled receptor 40
    • GPCR40
    • GPR 40
    • GPR40
    see all
  • Function
    Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.
  • Tissue specificity
    Expressed abundantly in pancreatic beta cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab45737 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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