Anti-GPCR GPR43 antibody (ab124272)

Overview

  • Product nameAnti-GPCR GPR43 antibody
    See all GPCR GPR43 primary antibodies
  • Description
    Rabbit polyclonal to GPCR GPR43
  • Tested applicationsSuitable for: ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to the C terminal region of Human GPCR GPR43.

  • Positive control
    • Human tonsil tissue; COS7 cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS is without Mg2+ and Ca2+
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab124272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF 1/100 - 1/500.

Target

  • FunctionReceptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.
  • Tissue specificityExpressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FFA2R antibody
    • Ffar2 antibody
    • FFAR2_HUMAN antibody
    • free fatty acid activated receptor 2 antibody
    • Free fatty acid receptor 2 antibody
    • G protein coupled receptor 43 antibody
    • G protein-coupled receptor 43 antibody
    • G-protein coupled receptor 43 antibody
    • GPR 43 antibody
    • GPR43 antibody
    see all

Anti-GPCR GPR43 antibody images

  • ab124272, at 5 µg/ml, staining GPCR GPR43 in formalin fixed, embedded Human tonsil tissue by Immunohistochemistry.
  • ab124272, at a 1/100 dilution, staining GPCR GPR43 in COS7 cells by iImmunofluorescence.
    The image on the right is treated with the synthesized peptide.

References for Anti-GPCR GPR43 antibody (ab124272)

ab124272 has not yet been referenced specifically in any publications.

Product Wall

The homology of this immunogen sequence to mouse is not good, only about 60%. It is possible yet unlikely that ab124272 will cross react with mouse protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"