Anti-GPCR GPR78 antibody - Cytoplasmic domain (ab188992)

Overview

  • Product name
    Anti-GPCR GPR78 antibody - Cytoplasmic domain
    See all GPCR GPR78 primary antibodies
  • Description
    Rabbit polyclonal to GPCR GPR78 - Cytoplasmic domain
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human GPCR GPR78. 17 amino acids synthetic peptide from 3rd cytoplasmic domain.
    Database link: Q96P69

  • Positive control
    • Human placenta, villi tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab188992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 14 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function
    Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
  • Tissue specificity
    High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ98800 antibody
    • G protein coupled receptor GPR78 antibody
    • G-protein coupled receptor 78 antibody
    • GPR78 antibody
    • GPR78_HUMAN antibody
    • PRO19818 antibody
    • UNQ5925 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded human placenta, villi tissue labeling GPCR GPR78 with ab188992 at 14 µg/ml.

References

ab188992 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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