Overview

  • Product nameAnti-GPCR HM74 antibody
    See all GPCR HM74 primary antibodies
  • Description
    Rabbit polyclonal to GPCR HM74
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human, Chimpanzee
  • Immunogen

    A portion of amino acids 1-50 of human GPCR HM74

  • Positive control
    • Human liver lysate. Human spleen tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.05% Sodium azide
    Constituents: 0.2% Gelatin, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab72112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
IHC-P Use a concentration of 10 µg/ml.

Target

  • FunctionReceptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.
  • Tissue specificityExpression largely restricted to adipose tissue and spleen.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor 109B antibody
    • G protein coupled receptor HM74 antibody
    • G protein coupled receptor HM74B antibody
    • G-protein coupled receptor 109B antibody
    • G-protein coupled receptor HM74 antibody
    • G-protein coupled receptor HM74B antibody
    • GPR109B antibody
    • HCA3 antibody
    • HCAR3 antibody
    • HCAR3_HUMAN antibody
    • HM74 antibody
    • HM74B antibody
    • Hydroxycarboxylic acid receptor 3 antibody
    • Niacin receptor 2 antibody
    • NIACR2 antibody
    • Nicotinic acid receptor 2 antibody
    • Puma g antibody
    • PUMAG antibody
    see all

Anti-GPCR HM74 antibody images

  • Anti-GPCR HM74 antibody (ab72112) at 1 µg/ml + human liver lysate

    Predicted band size : 45 kDa
    Observed band size : 45 kDa
    Additional bands at : 120 kDa,42 kDa. We are unsure as to the identity of these extra bands.
  • Analysis of GPCR HM74 expression in human spleen using ab72112 at 10 ug/ml.

References for Anti-GPCR HM74 antibody (ab72112)

ab72112 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"