Anti-GPCR HM74 antibody - N-terminal (ab150507)

Overview

  • Product name
    Anti-GPCR HM74 antibody - N-terminal
    See all GPCR HM74 primary antibodies
  • Description
    Rabbit polyclonal to GPCR HM74 - N-terminal
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except HCAR2 (100%).
  • Tested applications
    Suitable for: ICC, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Gorilla
  • Immunogen

    Synthetic peptide, corresponding to 18 amino acids from the N terminal extracellular domain of Human GPCR HM74 (NP_006009.2).

  • Positive control
    • Human Adipocytes and Spleen tissues.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C.
  • Storage buffer
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab150507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.
IHC-P Use a concentration of 3 - 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.
  • Tissue specificity
    Expression largely restricted to adipose tissue and spleen.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor 109B antibody
    • G protein coupled receptor HM74 antibody
    • G protein coupled receptor HM74B antibody
    • G-protein coupled receptor 109B antibody
    • G-protein coupled receptor HM74 antibody
    • G-protein coupled receptor HM74B antibody
    • GPR109B antibody
    • HCA3 antibody
    • HCAR3 antibody
    • HCAR3_HUMAN antibody
    • HM74 antibody
    • HM74B antibody
    • Hydroxycarboxylic acid receptor 3 antibody
    • Niacin receptor 2 antibody
    • NIACR2 antibody
    • Nicotinic acid receptor 2 antibody
    • Puma g antibody
    • PUMAG antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Adipocytes labeling GPCR HM74 with ab150507 at 4 µg/ml.
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human Spleen tissue labeling GPCR HM74 with ab150507 at 4 µg/ml.

References

ab150507 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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