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Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250. Detects a band of approximately 52 kDa (predicted molecular weight: 42 kDa).Can be blocked with
Human GPCR RDC1 peptide (ab38088).
GPCR RCD1 is glycosylated so it is not unexpected that it runs higher than predicted (based on primary structure) in SDS PAGE.
Function Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
Tissue specificity Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells.
Sequence similarities Belongs to the G-protein coupled receptor 1 family.
Cellular localization Cell membrane.
Information by UniProt
atypical chemokine receptor 3 antibody
C X C chemokine receptor type 7 antibody
Anti-GPCR RDC1 antibody images
Western blot - GPCR RDC1 antibody (ab38089)
All lanes : Anti-GPCR RDC1 antibody (ab38089) at 1/250 dilution Lane 1 : Human Brain Tissue Lysate Lane 2 : Human Testis Tissue Lysate Lane 3 : Human Liver Tissue Lysate Lane 4 : Human Heart Tissue Lysate Lysates/proteins at 10 µg per lane. Secondary IRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilution Performed under reducing conditions. Predicted band size : 42 kDa Observed band size : 52 kDa ( why is the actual band size different from the predicted?)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GPCR RDC1 antibody (ab38089) This image is courtesy of an Abreview submitted by Antibody Solutions Ltd.
ab38089 staining pancreas (human and mouse) kidney (mouse and rat) and testis (rat and human) tissue sections by IHC-P. Sections were formaldehyde fixed and subjected to heat mediated antigen retrieval in citrate buffer (pH 6) prior to blocking in sequential (prediluted) peroxidase and protein block for 20 minutes at 20°C. The primary antibody was diluted 1/100 and incubated with the samples for 45 minutes at 20°C. A HRP-conjugated goat anti-rabbit anitbody was used as the secondary.
References for Anti-GPCR RDC1 antibody (ab38089)
This product has been referenced in:
et al. Stromal derived factor-1 (SDF-1) and its receptors CXCR4 and CXCR7 in endometrial cancer patients. PLoS One 9:e84629 (2014).
Read more (PubMed: 24416254) »
et al. CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis. PLoS One 9:e90400 (2014).
Read more (PubMed: 24594697) »
See all 6 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"