Overview

  • Product name
  • Description
    Rabbit polyclonal to GPCR TGR5
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Horse, Chimpanzee, Monkey
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to amino acids 302-322 of Human GPCR19.

  • Positive control
    • Human colon tissue; Human kidney lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab117414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 - 4 µg/ml. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
  • Tissue specificity
    Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • BG 37 antibody
    • BG37 antibody
    • G protein coupled bile acid receptor 1 antibody
    • G protein coupled bile acid receptor BG 37 antibody
    • G protein coupled bile acid receptor BG37 antibody
    • G-protein coupled bile acid receptor 1 antibody
    • G-protein coupled receptor GPCR19 antibody
    • GPBAR 1 antibody
    • GPBAR_HUMAN antibody
    • GPBAR1 antibody
    • GPCR 19 antibody
    • GPCR antibody
    • GPCR19 antibody
    • GPR 131 antibody
    • GPR131 antibody
    • hBG 37 antibody
    • hBG37 antibody
    • hGPCR 19 antibody
    • hGPCR19 antibody
    • M BAR antibody
    • M-BAR antibody
    • Membrane bile acid receptor antibody
    • Membrane type receptor for bile acids antibody
    • Membrane-type receptor for bile acids antibody
    • MGC40597 antibody
    • TGR 5 antibody
    • TGR5 antibody
    see all

Images

  • ab117414, at 10 ug/ml, staining GPCR TGR5 in Formalin-fixed, Paraffin-embedded Human Colon tissue by Immunohistochemistryfollowed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen
  • All lanes : Anti-GPCR TGR5 antibody (ab117414) at 3 µg/ml

    Lane 1 : Human kidney lysate
    Lane 2 : Human kidney lysate with immunizing peptide


    Predicted band size : 35 kDa

References

ab117414 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab117414.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up