Recombinant
RabMAb

Anti-GPCR TGR7 antibody [EPR10597] (ab155099)

Overview

  • Product name
    Anti-GPCR TGR7 antibody [EPR10597]
    See all GPCR TGR7 primary antibodies
  • Description
    Rabbit monoclonal [EPR10597] to GPCR TGR7
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human GPCR TGR7 (UniProt: Q8TDS7).

  • Positive control
    • Human testis, bladder, muscle and fetal heart lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab155099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 36 kDa.Can be blocked with GPCR TGR7 peptide (ab218717).
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
    • Cellular localization
      Cell membrane. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
    • Information by UniProt
    • Database links
    • Alternative names
      • Beta alanine receptor antibody
      • Beta-alanine receptor antibody
      • G protein coupled receptor TGR7 antibody
      • G-protein coupled receptor TGR7 antibody
      • mas related G protein coupled MRGD antibody
      • Mas related G protein coupled receptor member D antibody
      • MAS related GPR member D antibody
      • Mas-related G-protein coupled receptor member D antibody
      • MRGD antibody
      • Mrgprd antibody
      • MRGRD_HUMAN antibody
      • TGR7 antibody
      see all

    Images

    • All lanes : Anti-GPCR TGR7 antibody [EPR10597] (ab155099) at 1/1000 dilution

      Lane 1 : Human testis lysate
      Lane 2 : Human bladder lysate
      Lane 3 : Human muscle lysate
      Lane 4 : Human fetal heart lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 36 kDa

    References

    ab155099 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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