Overview

  • Product nameAnti-GPCR6A antibody
    See all GPCR6A primary antibodies
  • Description
    Rabbit polyclonal to GPCR6A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 862-926 of Human GPCR6A (NP_683766).

  • Positive control
    • Raji cells

Properties

Applications

Our Abpromise guarantee covers the use of ab96504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 105 kDa.

Target

  • FunctionReceptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
  • Tissue specificityIsoform 1 is expressed at high level in brain, skeletal muscle, testis, bone, calvaria, osteoblasts and leukocytes. Expressed at intermediate level in liver, heart, kidney and spleen. Expressed at low level in lung, pancreas, placenta and ovary. Not detected in thymus, prostate, small intestine, tongue and colon. Isoform 1 and isoform 2 are expressed in kidney at the same level. Isoform 2 is expressed at lower level than isoform 1 in the other tissues.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 3 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA86F4.3 antibody
    • G protein coupled receptor 33 antibody
    • G protein coupled receptor family C group 6 member A antibody
    • G-protein coupled receptor family C group 6 member A antibody
    • G-protein coupled receptor GPCR33 antibody
    • GPC6A_HUMAN antibody
    • GPCR 33 antibody
    • GPCR 6A antibody
    • GPCR antibody
    • GPCR33 antibody
    • GPR C6A antibody
    • GPRC 6A antibody
    • gprc6a antibody
    • hGPCR 33 antibody
    • hGPCR33 antibody
    • hGPRC6A antibody
    • OTTHUMP00000017075 antibody
    • Predicted with SOSUI analysis antibody
    • seven transmembrane helix receptor antibody
    see all

Anti-GPCR6A antibody images

  • Anti-GPCR6A antibody (ab96504) at 1/500 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 105 kDa

References for Anti-GPCR6A antibody (ab96504)

ab96504 has not yet been referenced specifically in any publications.

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