ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake.
Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.
Belongs to the myelin proteolipid protein family.
Cell membrane. Colocalizes with SERT at the plasma membrane.
Flow Cytometry - Anti-GPM6B antibody - Aminoterminal end (ab170519)
Flow cytometry analysis of CEM cells labeling GPM6B (green, right histogram), using ab170519 at a 1/10 dilution, and negative control cells (blue, left histogram). FITC-conjugated goat-anti-rabbit secondary antibody was used for the analysis.
Western blot - Anti-GPM6B antibody - Aminoterminal end (ab170519)
All lanes : Anti-GPM6B antibody - Aminoterminal end (ab170519) at 1/100 dilution
Lane 1 : ZR-75-1 cell lysates Lane 2 : CEM cell lysates