Overview

  • Product nameAnti-GPR56 antibody
    See all GPR56 primary antibodies
  • Description
    Rabbit polyclonal to GPR56
  • Tested applicationsSuitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the an internal sequence of Human GPR56

  • Positive control
    • WB: extracts from K562 cells. ICC/IF: MCF-7 cells.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab77515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 78 kDa.
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.

Target

  • FunctionCould be involved in cell-cell interactions.
  • Tissue specificityWidely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.
  • Involvement in diseasePolymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
  • Post-translational
    modifications
    The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 7 transmembrane protein with no EGF like N terminal domains 1 antibody
    • BFPP antibody
    • DKFZp781L1398 antibody
    • EGF TM7 like antibody
    • G protein coupled receptor 56 antibody
    • G-protein coupled receptor 56 antibody
    • GPR 56 antibody
    • Gpr56 antibody
    • GPR56_HUMAN antibody
    • Polymicrogyria bilateral frontoparietal antibody
    • Protein TM7XN1 antibody
    • TM7LN4 antibody
    • TM7XN1 antibody
    • TM7XN1 protein antibody
    see all

Anti-GPR56 antibody images

  • All lanes : Anti-GPR56 antibody (ab77515) at 1/500 dilution

    Lane 1 : Extracts from K562 cells
    Lane 2 : Extracts from K562 cells with immunizing peptide at 5 µg

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 78 kDa
    Observed band size : 78 kDa
  • Immunofluorescence analysis of MCF-7 cells using 1/500 - 1/1000 ab77515
    Left image: untreated.
    Right image: after pre-incubation twith immunizing peptide.

References for Anti-GPR56 antibody (ab77515)

ab77515 has not yet been referenced specifically in any publications.

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