Overview

  • Product nameAnti-GPRC5C antibody
    See all GPRC5C primary antibodies
  • Description
    Rabbit polyclonal to GPRC5C
  • SpecificityDetects endogenous levels of total GPRC5C protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from an internal region of Human GPRC5C

  • Positive control
    • Cos-7 cell extract RAW264.7 cell extract

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesAffinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
ELISA 1/5000.

Target

  • FunctionThis retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • Tissue specificityExpression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG).
  • Sequence similaritiesBelongs to the G-protein coupled receptor 3 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor family C group 5 member C antibody
    • G-protein coupled receptor family C group 5 member C antibody
    • GPC5C_HUMAN antibody
    • GPCR5C antibody
    • Gprc5c antibody
    • MGC131820 antibody
    • Orphan G protein coupled receptor antibody
    • RAIG-3 antibody
    • RAIG3 antibody
    • Retinoic acid responsive gene protein antibody
    • Retinoic acid-induced gene 3 protein antibody
    see all

Anti-GPRC5C antibody images

  • All lanes : Anti-GPRC5C antibody (ab75499) at 1/500 dilution

    Lane 1 : RAW264.7 cell extract
    Lane 2 : Cos-7 cell extract
    Lane 3 : RAW264.7 cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa
    Observed band size : 48 kDa
    Additional bands at : 100 kDa. We are unsure as to the identity of these extra bands.

References for Anti-GPRC5C antibody (ab75499)

ab75499 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"