Overview

  • Product name
    Anti-GPS2 antibody [clone 1E2]
    See all GPS2 primary antibodies
  • Description
    Mouse monoclonal [clone 1E2] to GPS2
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 161-311 of Human GPS2

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab53406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB 1/500 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

Target

  • Relevance
    GPS2(G-protein pathway suppressor 2), also called AMF1, is a human nuclear protein of 327 amino acids involved in G protein-mitogen-activated protein kinase(MAPK) signalling cascades. This protein is an integral subunit of the NCOR1-HDAC3(nuclear receptor corepressor 1-histone deacetylase 3) complex which inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1(activator protein 1) function.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • AMF 1 antibody
    • AMF1 antibody
    • G protein pathway suppressor 2 antibody
    • GPS 2 antibody

Images

  • Anti-GPS2 antibody [clone 1E2] (ab53406) at 1/500 dilution + HeLa cell lysates at 100 µg

    Secondary
    HRP-conjugated goat anti-mouse
    Developed using the ECL technique

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

References

This product has been referenced in:
  • Rössger K  et al. A closed-loop synthetic gene circuit for the treatment of diet-induced obesity in mice. Nat Commun 4:2825 (2013). WB ; Human . Read more (PubMed: 24281397) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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