Overview

  • Product nameAnti-GPSM1 antibody
    See all GPSM1 primary antibodies
  • Description
    Rabbit polyclonal to GPSM1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide between amino acids 446-476 from the central region of Human GPSM1 (NP_056412.4 , NP_001139110.1 , NP_001139111.1).

  • Positive control
    • NCI-H460 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 75 kDa.

Target

  • FunctionGuanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
  • Tissue specificityExpressed in intestinal cells.
  • Sequence similaritiesBelongs to the GPSM family.
    Contains 4 GoLoco domains.
    Contains 9 TPR repeats.
  • DomainThe GoLoco domains mediate interaction with G(i/o) alpha (By similarity). The GoLoco domains are essential for the GDI activity toward G(i/o) alpha.
  • Post-translational
    modifications
    Phosphorylation regulates interaction with G(i/o) alpha.
  • Cellular localizationCytoplasm > cytosol. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activator of G-protein signaling 3 antibody
    • AGS3 antibody
    • AGS3 homolog antibody
    • C10a antibody
    • G protein signaling modulator 1 (AGS3 like, C. elegans) antibody
    • G-protein-signaling modulator 1 antibody
    • GPSM1 antibody
    • GPSM1_HUMAN antibody
    see all

Anti-GPSM1 antibody images

  • Anti-GPSM1 antibody (ab113040) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 75 kDa

References for Anti-GPSM1 antibody (ab113040)

ab113040 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"