• Product name
  • Description
    Rabbit polyclonal to GRAF
  • Tested applications
    Suitable for: IHC-P, ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the sequence of human GRAF within aa 200-300

  • Positive control
    • Mouse brain tissue, Human cancer tissue (breast carcinoma).



Our Abpromise guarantee covers the use of ab37618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/1000.
WB Use at an assay dependent concentration. Detects a band of approximately 94 kDa (predicted molecular weight: 94 kDa).


  • Function
    GTPase-activating protein for RHOA and CDC42.
  • Involvement in disease
    Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
  • Sequence similarities
    Contains 1 PH domain.
    Contains 1 Rho-GAP domain.
    Contains 1 SH3 domain.
  • Cellular localization
    Cell junction > focal adhesion. Cytoplasm > cytoskeleton. Colocalizes with actin stress fibers and cortical actin structures.
  • Information by UniProt
  • Database links
  • Alternative names
    • arhgap26 antibody
    • FLJ42530 antibody
    • GRAF antibody
    • GRAF1 antibody
    • GTPase regulator associated with focal adhesion kinase antibody
    • GTPase regulator associated with focal adhesion kinase pp125(FAK) antibody
    • KIAA0621 antibody
    • oligophrenin 1 like protein antibody
    • Oligophrenin-1-like protein antibody
    • oligophrenin1like protein antibody
    • OPHN1L antibody
    • OPHN1L1 antibody
    • RHG26_HUMAN antibody
    • Rho GTPase activating protein 26 antibody
    • Rho GTPase activating protein26 antibody
    • Rho GTPase-activating protein 26 antibody
    • Rho-type GTPase-activating protein 26 antibody
    see all


  • Anti-GRAF antibody (ab37618) at 1/100 dilution + Mouse brain tissue lysate

    Predicted band size : 94 kDa
    Observed band size : 94 kDa
    Additional bands at : 30 kDa,37 kDa,60 kDa. We are unsure as to the identity of these extra bands.
  • Ab37618 at 1/50 staining formalin fixed, paraffin embedded Human cancer tissue (breast carcinoma) for the detesction of GRAF.


ab37618 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your reply.

I am sending a vial of the GFAP antibody, ab7260, free of charge on the order ***. This should ship out tonight and arrive tomorrow. I have removed the vial of ab7260 from your proforma, andthe updated proformahas be...

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Thank you for your reply and for sending the additional information.

It will be no problem to issue you a refund. There are a few ways that we can process this:

1) If you need a different antibody, I can just send you one free of ch...

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Thank you for contacting us and for letting us know about the problem with this antibody.

Thank you also for sending all of the protocol information and the Western blot images. Could you tell me what kind of lysis buffer and protease inhibit...

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