Anti-Grainyhead-like protein 1 homolog antibody (ab111582)

Overview

  • Product name
    Anti-Grainyhead-like protein 1 homolog antibody
    See all Grainyhead-like protein 1 homolog primary antibodies
  • Description
    Rabbit polyclonal to Grainyhead-like protein 1 homolog
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-208 of Human Grainyhead-like protein 1 homolog.

  • Positive control
    • NT2D1, U-87 MG and MCF7 cells and whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78.99% PBS, 1% BSA, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab111582 is purified by antigen affinity chromatography.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 70 kDa.
ICC/IF 1/100 - 1/500.

Target

  • Function
    Transcription factor. Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed. May play a role in development. May be involved in epidermal differentiation (By similarity). Binds and transactivates the EN1 promoter.
  • Tissue specificity
    Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Highly expressed in placental JEG-3 cells and at very low levels in non-steroidogenic cells. No expression detected in adrenal NCI-H295A cells.
  • Sequence similarities
    Belongs to the grh/CP2 family. Grainyhead subfamily.
  • Developmental stage
    Expressed in fetal liver and brain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Grainyhead-like protein 1 homolog antibody
    • grhl1 antibody
    • GRHL1_HUMAN antibody
    • LBP32 antibody
    • Mammalian grainyhead antibody
    • MGR antibody
    • NH32 antibody
    • TFCP2L2 antibody
    • Transcription factor CP2-like 2 antibody
    • Transcription factor LBP-32 antibody
    see all

Images

  • Anti-Grainyhead-like protein 1 homolog antibody (ab111582) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

    Predicted band size : 70 kDa
  • ab111582 at 1/500 dilution staining Grainyhead-like protein 1 homolog in Paraformaldehyde-fixed MCF7 cells by Immunofluorescence. Lower image shows cells co-stained with Hoechst 33342.

References

ab111582 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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