Anti-Gram Negative Endotoxin antibody [13-337.5] (ab41199)

Overview

  • Product nameAnti-Gram Negative Endotoxin antibody [13-337.5]
    See all Gram Negative Endotoxin primary antibodies
  • Description
    Mouse monoclonal [13-337.5] to Gram Negative Endotoxin
  • Specificityab41199 detects and quantitates gram negative endotoxin or cells that express endotoxin. ab41199 will detect E. coli J5 LPS, Klebsiella pneumoniae, Shigella sonnei, Salmonella typhimurium
  • Tested applicationsSuitable for: Indirect ELISAmore details
  • Species reactivity
    Cross reacts with
  • Immunogen

    Tissue/ cell preparation (E. coli O:111 B4 J5 cells).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: Azide free
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number13-337.5
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab41199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA Use at an assay dependent concentration.

Elisa titer: 1/25,600

Target

  • RelevanceEndotoxins are part of the outer membrane of the cell wall of gram negative bacteria. Endotoxins are invariably associated with gram negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxins are associated with lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram negative bacterial infections.
  • Cellular localizationCell Membrane
  • Alternative names
    • E coli LPS antibody

References for Anti-Gram Negative Endotoxin antibody [13-337.5] (ab41199)

ab41199 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"