Overview

  • Product nameAnti-Grancalcin antibody
  • Description
    Mouse monoclonal to Grancalcin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-218 of Human Grancalcin

Properties

Applications

Our Abpromise guarantee covers the use of ab57040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceGrancalcin is a calcium binding protein abundant in neutrophils and macrophages. It belongs to the penta EF hand subfamily of proteins which includes sorcin, calpain, and ALG2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule membrane fusion and degranulation.
    • Cellular localization50% cytoplasmic, the remainder being attached to the membranes and granules.
    • Database links
    • Alternative names
      • GCA antibody
      • GCL antibody

    Anti-Grancalcin antibody images



    • Predicted band size : 24 kDa
      Grancalcin antibody (ab57040) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.

    References for Anti-Grancalcin antibody (ab57040)

    ab57040 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57040.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"