Anti-Granulocytes antibody [SPM250], prediluted (ab17856)

Overview

  • Product nameAnti-Granulocytes antibody [SPM250], prediluted
    See all Granulocytes primary antibodies
  • Description
    Mouse monoclonal [SPM250] to Granulocytes, prediluted
  • SpecificityThis antibody reacts with early precursor and mature forms of human myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes.

  • Positive control
    • Tonsil or lymph node

Properties

Applications

Our Abpromise guarantee covers the use of ab17856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready-to-use for 30 min at RT. No special pretreatment is required for histochemical staining of formalin/paraffin tissues.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceGranulocytes are a type of white blood cell filled with microscopic granules that are little sacs containing enzymes, compounds that digest microorganisms. They are part of the innate immune system and have somewhat nonspecific, broad-based activity. They do not respond exclusively to specific antigens, as do B-cells and T-cells. Neutrophils, eosinophils and basophils are all types of granulocytes. They are named by the staining features of their granules in the laboratory: Neutrophils have "neutral" subtle granules; Eosinophils have prominent granules that stain readily with the acid dye eosin; and Basophils have prominent granules that stain readily basic (non acidic) dyes.

    Anti-Granulocytes antibody [SPM250], prediluted images

    • ab17856 (Myeloid cell marker) staining Granulocytes in formalin fixed paraffin (ab17856, 30min at RT) embedded human tonsil tissue.

    References for Anti-Granulocytes antibody [SPM250], prediluted (ab17856)

    ab17856 has not yet been referenced specifically in any publications.

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